What is the first-line treatment for anaphylactic shock?

Epinephrine is the first-line treatment for anaphylactic shock because it addresses the physiological effects of anaphylaxis effectively and quickly. Anaphylaxis is a severe, potentially life-threatening allergic reaction that can cause airway constriction, hypotension, and systemic vasodilation. Epinephrine acts as a potent vasoconstrictor, increases heart rate, and relaxes bronchial smooth muscle, which is critical in reversing the life-threatening symptoms of anaphylaxis.

Administering epinephrine can quickly alleviate respiratory distress, improve blood pressure, and counteract swelling. The prompt use of epinephrine is essential in managing anaphylactic shock effectively, leading to rapid improvement in the patient's condition.

While other interventions may be needed to support the patient (such as intravenous fluids for volume resuscitation, antihistamines for adjunctive treatment, and oxygen therapy if the patient is hypoxic), these do not replace the critical role of epinephrine in the acute management of anaphylaxis.